The cholera toxin; an extremely potent protein molecule elaborated by strains of Vibrio cholerae in the small intestine after ingestion of feces-contaminated water or food. It acts on epithelial cells to cause hypersecretion of chloride and bicarbonate and an outpouring of large quantities of fluid from the mucosal surface.

Microbiology. . 2009.

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  • Cholera — A devastating and sometimes lethal disease with intense vomiting and profuse watery diarrhea leading to dehydration which, unless immediately treated, may be fatal. Cholera was discovered in 1883 to be due to infection with Vibrio cholerae, a… …   Medical dictionary

  • Epidemien —   Epidemien sind Krankheiten (insbesondere Infektionskrankheiten), die in Intervallen, das heißt mit zeitlicher, aber auch örtlicher Begrenzung, auftreten und jeweils große Teile der Bevölkerung befallen. Es kann sich dabei um relativ harmlose… …   Universal-Lexikon

  • cholera toxin — an exotoxin produced by Vibrio cholerae; a protein enterotoxin that binds to the membrane of enteric cells and stimulates the adenylate cyclase system, causing the hypersecretion of chloride and bicarbonate ions seen in cholera. Called also… …   Medical dictionary

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